Bovine Thrombin

RMBIO thrombin from bovine plasma has a wide range of applications and is offered in various package sizes as a freeze-dried product, based on activity.

Bovine Thrombin
  • As a coagulation protein, may be used for various clotting studies.
  • Defibrination of human plasma, producing serum matrices to be used as controls and standards.
  • Useful in polyclonal antibody production
  • 60-200 US units/mg protein
  • Bovine thrombin is provided as a lyophilized powder with specific NIH units/vial or at customers’ specification
  • We fractionate the thrombin fraction using a highly effective series of extraction and chromatographic filtration steps to retain maximum product potency.
  • Final solution is filtered aseptically through 0.2 µ filters before lyophilization
  • Storage conditions: 2 – 8° C.

Bovine thrombin is an enzyme that activates factor XIII and converts fibrogen into fibrin. Therefore it's primary use is in the defibrination of plasma to produce serum matrixes to be used as controls and standards.

Bovine thrombin from RMBIO is produced as a lyophilized powder that is activated from highly purified prothrombin. Our final product is derived from bovine raw material through a proprietary fractionation process. There are several methods available to determine the specific activity of thrombin. RMBIO employs a method recommended by NIH and it is based on a visual observation of clotting times. NIH units are defined as the amount of enzyme which clots 1.0% fibrinogen solution or plasma with identical reactivity in 15 seconds at 37oC, pH 7.2 ± 0.1 at sodium chloride concentration of 0.15M (normal saline).

We use only the highest quality thrombin from bovine plasma that has been sourced from Australia/New Zealand or domestically. Bovine Thrombin can be customized for your every research need at our hi-tech and modern facility in Missoula, MT.

Safe Sourced and Enhanced Manufacturing Processes

Bovine Thrombin specific product test requirements and typical values are given below:

Parameter Method Specification
pH (1% solution) pH Meter 6.5 - 7.5
Thrombin Activity Coagulation 50,000 - 150,000 units/g powder
Specific Thrombin Activity Clotting Assay 90 - 250 US units/mg protein
Salts Glycine, Sodium Chloride, Calcium Chloride
Reconstitution Normal Saline
Parameter Method Specification
pH (1% solution) pH Meter 6.5 - 7.5
Thrombin Activity Coagulation 50,000 - 150,000 units/g powder
Specific Thrombin Activity Clotting Assay 90 - 250 US units/mg protein
Salts Glycine, Sodium Chloride, Calcium Chloride
Reconstitution Normal Saline

Documents

Order today and you will receive your Bovine Thrombin on the next business day.

Purified from validated raw materials of the United States

Catalog Number: BTB-BBZ
Size Qty Price
250 KU $365.00
500 KU Out-of-Stock $850.00
1 MU $940.00

Purified from validated raw materials of Australia and New Zealand.

Catalog Number: BTB-ABZ

Special Order

BTB-ABZ is a special order item. Please contact our team for pricing and availability.

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