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“Fetalgro is an economically appealing choice as a Fetal Bovine Serum replacement for culturing suitable cell lines.” — US National Library of Medicine
IgG Depleted Fetal Bovine Serum (FBS)
Our IgG Depleted FBS is manufactured from our premium US sourced FBS. Using a proprietary chromatography process we manufacture IgG Depleted FBS with an IgG content <5.0 ug/mL in lot sizes up to 500 liters.
- Our IgG Depleted Fetal Bovine Serum has an IgG of below 5.0.
- Triple 0.1 µ filtered
- All fetal bovine serum is fully traceable and is sourced from audited suppliers
- Large lot sizes of up to 500 Liters
- It is found in monoclonal antibody production that IgG depleted Fetal Bovine Serum performs very well.
- Standard IgG Depleted FBS serum packaged in 500mL or 1 L bottles. Custom packages are also available.
- Storage conditions: ≤ -10° C
RMBIO uses our premium grade FBS as the starting material for our IgG Depleted FBS. We then reduce the IgG content of the FBS utilizing a series of proprietary chromotography procedures. The result is FBS with substantially reduced IgG levels, and cell growth performanace comparable to the starting material. The average level of IgG in normal, Bovine Fetal Calf Serum is approximately 70-300 µg/mL. RMBIO’s IgG Depleted FBS is manufactured to meet the stringent specification of no more than 5 µg/mL, while maintaining cellular viability and biological growth-promoting activity.
Safe Sourced and Enhanced Manufacturing Processes
IgG Depleted Fetal Bovine Serum (FBS) specific product test requirements and typical values are given below:
| Parameter | Method | Specification |
|---|---|---|
| IgG | ELISA | < 5.0 |
| Total Protein | Colorimetric Assay | 3.0 - 4.5 g/dL |
| Osmolality | By Osmometer | 280 - 340 mOsm/Kg |
| pH | pH Meter | 7.0 - 8.0 |
| Hemoglobin | Contract Lab | < 25 mg/dl |
| Albumin | Contract Lab | 1.7 - 3.4 g/dL |
| Endotoxin | LAL | < 10 |
| IgG | ELISA | As Reported |
| Electrophoretic ID | Gel Electrophoresis | Characteristic |
| Other Parameters | Comprehensive Chemistry Testing | As Reported |
Documents
Certificate of Analysis
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Samples
Our products will improve the performance of your science. Our samples will tell you the same thing. Grab some now. Request a sample →Related Products
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Related Articles
Basics of IgG Depleted or Low IgG Fetal Bovine Serum (FBS)
This is one article in RMBIO’s Serum Treatment series which examines the benefits associated with treating fetal bovine and other animal serums with services including gamma irradiation, heat inactivation and IgG depletion. This article focuses specifically on the basics of IgG Depleted FBS.
