Cell Culture Supplements

Choose from a wide variety of high-quality cell culture supplements and replacements like fetal bovine serum, protein fractions, and Lipogro

RMBIO works with the world’s top pharmaceutical and biotechnology companies, supplying high quality, safely sourced, and high performing cell culture supplements. Choose from a wide range of products including fetal bovine serum and other animal sera, protein fractions, WFI, and our unique growth media supplement or replacement, Lipogro.

Our process starts with safely sourced raw material. Bovine serum comes from herds based in Australia New Zealand, Brazil, China and the United States. Pig, horse, and goat serum is sourced from carefully monitored herds. All collections are carried out by trained technicians following our rigorous protocol.

RMBIO recognizes that timeliness is critical in pharmaceutical production. We have developed a strong supply chain, which allows us to maintain a steady quantity of cell culture supplements. We can deliver the ingredients for your media and protein production when you need them. RMBIO products also remain highly consistent lot to lot because our production process begins with large pooled quantities.

While RMBIO sera deliver on performance and consistency, we have also developed a unique product that can act as either a cell culture media supplement or a replacement. Lipogro is used in the production of monoclonal antibodies for human therapeutic use. Research data has shown that Lipogro will:

  • Increase cell growth
  • Increase and maintain cell viability
  • Increase protein production

Choosing Lipogro as a cell growth supplement can boost performance and reduce your use of cell growth media. Or you could skip the serum and simply use Lipogro for expedient, satisfactory results.

RMBIO also produces IgG Free BSA for use in cell culture. Our IgG Free BSA provides the most purified form of BSA for cell culture applications, although we do offer numerous specialty grades of BSA including fatty-acid poor.

Transferrin is another popular product at RMBIO. This highly purified protein is useful as a cell culture supplement in almost any media formulation, and it is a vital part of serum-free and serum-reduced media.

Finally, in addition to our range of industry standard products, RMBIO specializes in delivering customized proteins to meet the exact specifications of our clients. We work with a variety of raw materials and provide specialized processing to ensure that you get the exact product you need for success. Contact an RMBIO representative today to discuss your custom order.

Read more
Lipogro<sup>&reg;</sup> Bovine Cholesterol Concentrate

Lipogro® Bovine Cholesterol Concentrate

RMBIO produces Lipogro lipoprotein solution, an industry-leading cell culture supplement or FBS substitute. Lipogro increases your cell culture media effectiveness while reducing your operating costs.

Fetalgro<sup>&reg;</sup> Bovine Growth Serum (BGS)

Fetalgro® Bovine Growth Serum (BGS)

Fetalgro® is our proprietary bovine growth serum (BGS) supplemented with additives that match or outperform FBS' cell growth capabilities in many cell lines including CHO and Vero.

Fetal Bovine Serum - FBS

Fetal Bovine Serum - FBS

RMBIO’s Fetal Bovine Serum (FBS) promotes steady, healthy cell growth. We can source our FBS cell culture medium supplement from Australia, New Zealand, the US, as well as USDA approved regions in North America. We provide a Certificate of Analysis for all lots.

IgG Depleted Fetal Bovine Serum (FBS)

IgG Depleted Fetal Bovine Serum (FBS)

Our IgG Depleted FBS is manufactured from our premium US sourced FBS. Using a proprietary chromatography process we manufacture IgG Depleted FBS with an IgG content <5.0 ug/mL in lot sizes up to 500 liters.

Gamma Irradiated Fetal Bovine Serum (FBS)

Gamma Irradiated Fetal Bovine Serum (FBS)

We use our premium FBS as starting material and then use our qualified supplier to apply a dose of irradiation in a range of 25k - 50kGy.

Heat Inactivated Fetal Bovine Serum (FBS)

Heat Inactivated Fetal Bovine Serum (FBS)

Heat inactivated fetal bovine serum (FBS) is manufactured using our premium source fetal bovine serum, which is then heated to 56 degrees celsius for 30 minutes. The heat inactivation occurs in a water bath under a process controlled by an SOP to ensure consistency.

Dialyzed Fetal Bovine Serum (FBS)

Dialyzed Fetal Bovine Serum (FBS)

Our dialyzed FBS is manufactured from our premium US sourced FBS using a proprietary process.

Charcoal Stripped Fetal Bovine Serum (FBS)

Charcoal Stripped Fetal Bovine Serum (FBS)

Our charcoal stripped FBS is manufactured from our premium US sourced FBS using a proprietary process.

Bovine Serum Albumin IgG Free - BSA

Bovine Serum Albumin IgG Free - BSA

Ensure that your cell cultures and other biochemical processes are successful by using RMBIO’s IgG free bovine serum albumin. This cell nutrient is manufactured using advanced techniques to completely eliminate IgG.

Newborn Calf Serum - NBCS (Bovine)

Newborn Calf Serum - NBCS (Bovine)

RMBIO provides bovine Newborn Calf Serum (NBCS) for use in a variety of cell culture media. We source NBCS from New Zealand and the US. For our US-origin materials, we ensure that NBCS is derived from bovine that are 10 days postpartum or fewer to maintain a consistent final product.

Bovine Serum Albumin Standard Heat Shock - BSA

Bovine Serum Albumin Standard Heat Shock - BSA

Standard bovine serum albumin from RMBIO is a high quality protein stabilizer. We produce bovine serum albumin (BSA) using either US or Australian/New Zealand sourced raw material, so we can provide bovine serum albumin for either pharmaceutical or diagnostic uses. Our heat shock BSA is available in both liquid and lyophilized form, with the liquid BSA concentrated to 30% with sodium azide.

Water For Injection, USP/EP Grade, Sterile

Water For Injection, USP/EP Grade, Sterile

RMBIO USP/EP Water for Injection Grade product is manufactured to meet both the USP and EP specifications.

Water For Injection (WFI), USP, Sterile

Water For Injection (WFI), USP, Sterile

RMBIO Water For Injection (WFI) is highly purified water rendered specifically for scientific applications. WFI is delivered in containers with universal connectors to improve our customers experience and protect the integrity of our product.

Water For Irrigation (WIR), USP, Sterile

Water For Irrigation (WIR), USP, Sterile

RMBIO’s Water for Irrigation (WIR), USP is a sterile fluid or solvent that is perfect for buffer preparation where WFI water is not required.

Purified Water, USP, Sterile&nbsp;

Purified Water, USP, Sterile 

Our USP Purified Water is available in sterile and non-sterile formats, and complies with the USP monograph for purified water.

Molecular Biology Certified Water

Molecular Biology Certified Water

Our Molecular Grade Water is quality tested and certified RNase, DNase, and protease free.

ACS Reagent Grade Water

ACS Reagent Grade Water

RMBIO also produces Reagent Grade water for very precise laboratory analysis and sensitive diagnostic needs.

ASTM Type II&nbsp;Reagent Grade Water

ASTM Type II Reagent Grade Water

RMBIO manufactures Reagent Grade water for very precise laboratory analysis and sensitive diagnostic needs.

Cell&nbsp;&amp; Molecular Ultra Pure Water, Sterile

Cell & Molecular Ultra Pure Water, Sterile

A universal, ultrapure water for your most sensitive research applications. It is suitable for cell culture applications, media and reagent grade preparation.

Bovine Serum Albumin Fatty Acid Poor - BSA

Bovine Serum Albumin Fatty Acid Poor - BSA

Our fatty acid poor bovine serum albumin is manufactured using proprietary methodology. This methodology has been continually improved over decades of experience, and it results in a bovine serum albumin with fatty acid levels that are present in trace amounts.

Formula Fed Calf Serum - Bovine Calf Serum

Formula Fed Calf Serum - Bovine Calf Serum

RMBIO produces high quality, low hemoglobin US sourced Formula Fed Calf Serum for use in cell culture media. Formula Fed Bovine Calf Serum provides the start for successful cell growth at a fraction of the price of Fetal Bovine Serum due to its availability.

Iron Fortified Calf Serum

Iron Fortified Calf Serum

RMBIO produces US origin Iron Supplemented Calf Serum for use in cell culture media. Supplementing iron to Formula Fed Calf Serum can enhance serum transferrin levels and in many cases be a much less expensive alternative to FBS in promoting cell growth and its effectiveness.

Pig Serum - Porcine Serum

Pig Serum - Porcine Serum

One of the only natural pig serum providers, RMBIO sources our porcine serum from farms in the US. Porcine serum is ideal for vaccine production as well as cell culture.

Pig Serum - Porcine Serum, Gamma Irradiated and Heat Inactivated

Pig Serum - Porcine Serum, Gamma Irradiated and Heat Inactivated

Our most popular treatments for RMBIO porcine serum are gamma irradiation and heat inactivation. This standard stock sku combines both in our natural pig serum sourced from the US.

Donor Horse Serum - Equine Serum

Donor Horse Serum - Equine Serum

Donor horse serum from RMBIO is derived from US-origin or Australia/New Zealand, veterinary-inspected and controlled herds. Equine serum is ideal for use as cell culture medium and in veterinary biologics.

Donor Horse/Equine Serum, Gamma Irradiated

Donor Horse/Equine Serum, Gamma Irradiated

Donor horse serum from RMBIO is derived from US-origin or Australia/New Zealand, veterinary-inspected and controlled herds. Equine serum is ideal for use as cell culture medium and in veterinary biologics. This product has been gamma irradiated to meet the needs of our customers.

Bovine Fibrinogen

Bovine Fibrinogen

Our bovine fibrinogen is available in lyophilized powder. It is manufactured from bovine plasma sourced in the US using our proprietary process.

Adult Bovine Serum

Adult Bovine Serum

Adult bovine serum is collected by trained technicians and further processed in RMBIO’s state of the art facility. We source our adult bovine serum from the US, as well as Australia and New Zealand and carefully control each stage of the process.

Donor Goat Serum

Donor Goat Serum

RMBIO collects donor goat serum from healthy adult animals in carefully controlled herds. We pool the goat serum and filter it to produce high-quality and highly consistent lots.

Human Serum

Human Serum

RMBIO provides human serum for research, cell culture, and diagnostic purposes. Human serum from RMBIO undergoes rigorous quality control screening.

Human Serum Albumin

Human Serum Albumin

RMBIO offers high quality human serum albumin sourced from blood donors who are carefully screened. Human serum albumin is a potential replacement for bovine serum albumin.

Bovine Trypsin

Bovine Trypsin

Our bovine trypsin is available in liquid and lyophilized forms. It is manufactured from material sourced in the US using our proprietary process.

Porcine Trypsin

Porcine Trypsin

Our porcine trypsin is available in liquid and lyophilized forms. It is manufactured from material sourced in the US using our proprietary process.

Bovine Gamma Globulin

Bovine Gamma Globulin

Bovine Gamma Globulin from RMBIO is >= 95% pure and can be used in a number of immunoassays or as a control solution. Our bovine gamma globulin is provided as a powder and has been purified from either domestic or Australian and New Zealand bovine raw material.

Normal Saline, Sodium Chloride, 0.9%

Normal Saline, Sodium Chloride, 0.9%

RMBIO manufactures Sodium Chloride, 0.9% (w/v) Isotonic Saline utilizing USP grade NaCl and formulated in USP Water For Injection quality water.

Phosphate-Buffered Saline (PBS) 1X w/o Ca &amp; Mg

Phosphate-Buffered Saline (PBS) 1X w/o Ca & Mg

RMBIO manufactures PBS utilizing USP raw materials formulated in USP Water for Injection quality water.