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Gamma irradiated Newborn Bovine Calf Serum in a transparent 500 milliliter bottle.

Newborn Bovine Calf Serum - Gamma Irradiated

RMBIO’s bovine Newborn Calf Serum (NBS) is a high-quality supplement for use in a variety of cell culture media. NBS can serve a low-cost alternative to FBS while providing many of the same nutrients.
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Catalog Number : NBS-BTG
Purified from validated raw materials of the United States
Size
Price
Quantity
500 ML
$100.00
50 ML
$30.00
 
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Product Details

We source NBS from audited suppliers within the US. Our NBS is manufactured and processed according to the highest standards and is carefully monitored to ensure product safety and performance. These standards are built in to RMBIO's entire supply chain. After filtration and filling, the NBS is gamma irradiated at an industry standard dose of 25-40kGy.

  • Average endotoxin level*: < 2 EU/ml (specification = ≤ 35 EU/ml)
  • Average hemoglobin level*: < 20 mg/dl (specification = < 30 mg/dL)
  • 9CFR tested
  • 0.2 µm filtered
  • Gamma irradiated at a dose of 25-40kGy
  • Manufactured at GMP compliant and FDA registered facility
  • Standard newborn calf serum packaged in 500mL or 1 L bottles. Custom packages are also available.
  • Storage conditions: ≤ -10° C

*Data based on last 10 lots produced.



Gamma Irradiation 101
Gamma irradiation is a physical inactivation approach used to achieve pathogen reduction in the serum. This mitigates risk from low-level contaminants that may not be detected through viral or mycoplasma testing. RMBIO serum is gamma irradiated via controlled exposure to Cobalt 60 at an industry standard dose of 25-40kGy. Most typical viral contaminants of bovine serum are readily inactivated at this irradiation range. Advantages of gamma irradiation include:

  • No potential for residual contaminants
  • Widely accepted by pharmaceutical and research industries
  • Accepted by regulatory agencies
  • Minimal effect on product performance
  • Effective virus inactivation

Newborn Calf Serum specific product test requirements and typical values are given below:


Parameter Method Specification
Total Protein Chemistry Analyzer 3.0 - 6.5 g/dL
Osmolality By Osmometer 240 - 360 mOsm/Kg
pH pH Meter 6.5 - 8.5
Hemoglobin Spectro. Assay < 30 mg/dl
Endotoxin LAL ≤ 35 EU/ml
Sterility, Mycoplasma, and Viral Analysis 9CFR 113.26, 28, 53 Tested
Electrophoretic ID Gel Electrophoresis Characteristic
Other Parameters Comprehensive Chemistry Testing As Reported
Gamma Irradiation 25-40kGy
Parameter Method Specification
Total Protein Chemistry Analyzer 3.0 - 6.0 g/dL
Osmolality By Osmometer 240 - 360 mOsm/Kg
pH pH Meter 6.5 - 8.5
Hemoglobin Spectro. Assay < 30 mg/dl
Endotoxin LAL ≤ 35 EU/ml
Sterility, Mycoplasma, and Viral Analysis 9CFR 113.26, 28, 53 Tested
Electrophoretic ID Gel Electrophoresis Characteristic

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